Ibhalansi yamanani e-pH emzimbeni womuntu

En Ok Pool Reform, kulesi sigaba ngaphakathi kwe Izinga le-pH lamachibi okubhukuda sizophatha i Ibhalansi yamanani e-pH emzimbeni womuntu.

Ibhalansi yamanani e-pH emzimbeni womuntu

Lisho ukuthini inani le-pH emzimbeni womuntu?

I-pH isikali esiklanyelwe ukukala i-alkalinity noma i-acidity yento, futhi ikhombisa iphesenti le-hydrogen eliqukethwe kuyo.

Kumele kuqashelwe ukuthi amangqamuzana omzimba adinga i-pH ene-alkaline kancane (phakathi kuka-7 no-7,4) ukuze asebenze kahle. Ngempela, usokhemisi uLinus Pauling, owazuza imiklomelo emibili kaNobel, ukuqinisekisile ukuthi ukugcina umzimba ku-alkaline pH kuyisihluthulelo sokujabulela impilo enhle.

Ukucatshangelwa kwezinto eziphilayo yenani le-pH

Ukucatshangelwa kwebhayoloji yenani le-pH: Izinhlobo ze-Tautomeric zama-purines nama-pyrimidines

• I-Tautomerization iwuhlobo olukhethekile lwe-isomerism lapho i-proton ifudukela ohlangothini olulodwa futhi isibopho esihlangene sihamba siye kolunye uhlangothi ngaphakathi kwe-molecule.
• Izisekelo ze-Purine ne-pyrimidine zikhona ngezindlela ezahlukene ze-tautomerized kuye nge-pH.
• Aqondile, enziwe tautomerized ku-pH yomzimba engaba ngu-7,4, futhi abalulekile ekubopheni i-hydrogen yamapheya ayisisekelo ahambisanayo ku-DNA helices ephindwe kabili nemicu ye-RNA. Ngakho-ke, i-pH igcina izimo zemvelo ezinezinhlangothi ezintathu zama-nucleic acid.

Intshisekelo yebhayoloji yenani le-pH ye-isoelectric

• I-PH ithonya i-ionization yamaqembu e-polar e-ionzable wama-amino acid, amaprotheni, ama-nucleic acid, ama-phospholipids, nama-mucopolysaccharides.
• Kwi-pH ethile, ebizwa nge-pH ye-isoelectric ye-molecule, i-molecule ngayinye ikhona njengama-dipole zwitterion aqukethe amaqembu e-cationic ne-anionic acid kanye nokushajwa okuphelele kwenetha.
• Ama-ion e-Zwitter awafuduki ezindaweni zikagesi futhi awanathisa kalula ngokuhlanganisa ngenxa yokucijwa okuncane kwe-electrostatic.

Imisebenzi ehambisana namazinga e-pH emzimbeni

• Okokuqala, amasistimu wokushisa: Amaprotheni ayingxenye yesistimu ye-buffer yokulawula amazinga e-pH.
• Ukulawula Ukuphefumula: I-pH yegazi ngaphansi kwezimo ezijwayelekile ingu-7,4. Kodwa-ke, i-CO2 ihlukanisa ibe yi-carbonic acid ezicutshini. Ngakho-ke, ukuba khona kwe-CO2 eningi kwenza igazi libe ne-asidi. Kungakho lapho sibambe umoya isikhathi eside, amazinga e-CO2 akhuphuka egazini, ehlise i-pH yethu futhi asenze siphelelwe amandla. Ngakolunye uhlangothi, ngesikhathi se-alkalosis noma i-pH eyengeziwe, ukuphefumula kunganciphisa ukwandisa amazinga e-CO2 futhi kunciphise i-alkalinity. Kodwa-ke, izinga eliphansi lokuphefumula lingaholela emazingeni aphansi komoyampilo okungaba yingozi. Ngakho-ke, ukuphefumula kunikeza ukulawula okubalulekile kokulawula amazinga e-pH.
• Uhlelo lwezinso lulawula i-pH yoketshezi oluphuma ngaphandle.
• Ngakolunye uhlangothi futhi inikeza isivikelo ezifweni ezibangelwa amagciwane. Nge-pH ene-acidic izimo ezifanele zinikezwa ukuze kuphile izitshalo ezivamile zesifunda. Amagciwane alihlanganisayo akha uhlelo lokuzivikela olubaluleke kakhulu ngokumelene nama-pathogenic agents avela kwamanye amazwe.
• Futhi ekugcineni, i-pH isebenza njenge umvikeli ngokumelene nezixazululo ze-alkaline ezifweni zesikhumba, njengoba isigqoko se-asidi esivikelayo sesikhumba sinesibopho sokusigcina sivikelekile emithonyeni yemvelo engayilimaza. Ivikela isikhumba ngokuqondile emiphumeleni yezixazululo ze-alkaline (isibonelo, lapho ugeza ngezinsipho ze-alkaline, i-bleach ...). Ngokungaqondile, iyayivikela ekukhuleni ngamagciwane noma isikhunta futhi ivimbele ukutheleleka.

Inani le-pH elifanelekile lomzimba womuntu

Inani le-pH elifanelekile emzimbeni womuntu

I-pH ekahle yomzimba womuntu i-7 nakuba ivamise ukuzungeza: 7.35-7.45.

Amanani e-pH oketshezi oluhlukahlukene lomzimba

I-pH yegazi lezinto eziphilayo iphakathi kuka-7.35 no-7.45 ngenani elimaphakathi elingu-7.4.

Udokotela uhlola ibhalansi ye-asidi-base yomuntu ngokukala i-pH namazinga e-carbon dioxide (i-asidi) ne-bicarbonate (isisekelo) egazini.

I-pH engaphansi kuka-7.35 i-acidosis futhi i-pH ephakeme kuno-7.45 ibizwa ngokuthi i-alkalosis.

• Ukuze uvimbele ukungalingani phakathi kwama-asidi nezisekelo ngesikhathi se-metabolism yansuku zonke, umzimba unezinhlelo ezihlukahlukene zokulawula. 
• Ngakho-ke, uma ufuna ulwazi mayelana nomthelela we-pH empilweni yethu yegazi, ungachofoza isixhumanisi esilandelayo: Ibhalansi yama-asidi nezisekelo kuketshezi lomzimba wemizimba yethu ibaluleke kakhulu.

Nakuba i-pH yegazi isuka ku-7,35 iye ku-7,45, i-pH yolunye uketshezi lomzimba ihlukile.

• Ngokuqondene ne-pH yoketshezi lomzimba, iyahluka kancane phakathi koketshezi lwezingxenye ezahlukene zomzimba.
• Ngokwezinga lapho egazini le-arterial, i-pH ingu-7,4, egazini le-venous kanye noketshezi oluphakathi nendawo ingu-7,35, kuyilapho i-pH yeselula emaphakathi ingu-7,0.
• Okwamanje, ku-physiology yokuphefumula sibona ukuthi igazi le-venous liqukethe i-CO eyengeziwe₂ kunegazi le-arterial nokuthi kukhona ukuhlobana okuqondile phakathi kwe-CO₂ kanye ne-pH, ukuze i-CO eyengeziwe₂, i-pH ephansi. Lokhu kuchaza umehluko ku-pH phakathi kwegazi le-venous ne-arterial.

Esiswini, i-pH iphakathi kuka-1,5 - 3. I-acidic ephindwe izikhathi ezingu-100.000 kunegazi.

Inani le-pH elikahle esiswini

I-pH ibonisa izinga lama-H+ ion, nge-pH ephansi ebonisa ama-H+ ion amaningi kakhulu kanye ne-pH ephezulu ebonisa ama-OH- ion amaningi kakhulu. Uma amazinga e-pH ehla ngaphansi kuka-6,9, kungaholela ekukhomeni. Nokho, uketshezi oluhlukene lomzimba lunamanani ahlukene we-pH.

• I-pH yamathe iphakathi kuka-6,5 no-7,5. Ngemva kokugwinya, ukudla kufinyelela esiswini lapho izingxenye ezingenhla neziphansi zesisu zinezilinganiso ze-pH ezihlukene.
• Ingxenye engenhla ine-pH engu-4 kuya ku-6,5, kanti ingxenye engezansi ine-acidic kakhulu ne-pH engu-1,5 kuya ku-4,0.
• Ibe isingena emathunjini ane-alkaline kancane, ene-pH engu-7-8.5. Ukugcina amanani e-pH yezifunda ezahlukahlukene kubalulekile emsebenzini wazo.

i-pH yamanzi okuphuza

i-pH namanzi amasha

• Umzimba womuntu wakhiwe ngamanzi angamaphesenti angama-70. Ngakho-ke akumangazi ukuthi i-H2O idlala indima ebalulekile ekusimamiseni izinga lethu le-pH lemvelo. Lokho kungesinye sezizathu esenza sihlale sitshelwa ukuthi siphuze amanzi amaningi. Kodwa hhayi nje noma yimaphi amanzi. Amanzi ane-pH ephakathi kuka-7,2 no-7,8 alungele ukugcina impilo enhle.
• Lapho siphuza uketshezi olune-asidi kakhulu noma olune-alkali kakhulu, lungaphazamisa ukulinganisela komzimba okuthambile, okungaholela ekukhuleni kwamagciwane, amagciwane, isikhunta, imvubelo, nezilokazane. Umugqa ongezansi? Khetha amanzi akho ngokuhlakanipha futhi uwaphuze kakhulu.

I-pH yamanzi okuphuza: 6.5 kuya ku-8.5

• El pH eyamukelekayo ku ukuphuza amanzi ihluka phakathi kuka-6.5 kuya ku-8.5 njengenani lomhlahlandlela (^{Jimenez, 2001}). Ngokuvumelana ne ^{Galvin (2003}), Okwe amanzi ukusetshenziswa komuntu, amanani okwedlulele angabangela ukucasuka kulwelwesi lwamafinyila, ukucasuka ezithweni zangaphakathi kanye nezinqubo zezilonda.

pH demineralized amanzi

ph ukubaluleka kwamanzi distilled

• Amanzi ahlanzekile, ngokwencazelo, ane-acidic kancane futhi amanzi acwecwe azoba ne-pH engaba ngu-5,8. Isizathu siwukuthi amanzi distilled ancibilikisa carbon dioxide emoyeni.
• Incibilikisa i-carbon dioxide ize ibe sekulinganisweni okuguquguqukayo nomkhathi. 4.5-5.0 Ukuhlanzeka okuphezulu kwalezo zithombe ezimile kuvame ukuba ngu-1.0 MWcm; futhi njengoba kungekho ukuvikeleka ekuncibilikeni kwe-carbon dioxide (CO2) ku-distillate, i-pH ivamise ukuba ngu-4.5-5.0.

Ibhalansi ye-pH ye-repercussion

Ibhalansi ye-acid-base yezinga le-pH emzimbeni

Ukulawulwa kwebhalansi ye-acid-base, okungukuthi, i-pH, ibalulekile emzimbeni.

Ama-Enzyme nezinqubo zamakhemikhali ezinto eziphilayo zisebenza kahle kuphela phakathi kwebanga elithile le-pH, ngaleyo ndlela kucekele phansi amanye ama-enzyme uma izinga le-acid-base oketshezini lomzimba lingejwayelekile.

i-alkaline yomzimba womuntu pH

Ukubaluleka kwebhalansi ye-pH: Ukugcina i-pH ingaphezulu kuka-7 noma i-alkaline kuyisiqinisekiso esingcono kakhulu sezempilo.

ph amanani ajwayelekile ezempilo

• Imizimba yethu iphila futhi ife ezingeni lamangqamuzana futhi amaseli kufanele agcine i-alkalinity ukuze asebenze futhi ahlale ephila. Isimo se-acidic sibangela ukuntuleka komoya-mpilo ezingeni lamangqamuzana.

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Ukubaluleka kwe-pH empilweni

wingspan ph nempilo

Kamuva, incazelo emfushane yomqondo wamandla e-hydrogen nokubaluleka kwayo empilweni.

Ukuphazamiseka kokungalingani ph ezempilo amanani ajwayelekile

Ibhalansi yama-asidi nezisekelo kuketshezi lomzimba wemizimba yethu ibaluleke kakhulu.

• Ukungalingani kungabangela i-acidosis (i-acidity eyengeziwe) noma i-alkalosis (isisekelo eseqile) emzimbeni wethu, ukuphazamiseka kwe-metabolic, okubonakala ngezimpawu ukuthi ngaphandle kokwelashwa kungaba nemiphumela emibi kakhulu.
• Ngaphezu kwalokho, ukwakheka nokukhula kwamagciwane ekudleni kudinga imisoco, amanzi, izinga lokushisa elanele kanye namazinga athile e-pH. Amanani e-pH ekudleni asuka ku-1 kuye ku-14, kanti u-7 uthathwa njengenani elingathathi hlangothi. Uma izinga le-pH ekudleni lingaphezu kuka-7, kuthiwa line-alkaline; ngakolunye uhlangothi, inani elingaphansi kuka-7 libonisa ukudla okune-acidic.

I-pH engaphansi kuka-7,4 ayilungile futhi inikeza indawo ekahle yamagciwane, isikhunta kanye nokukhula kwegciwane.

I-Acidosis: Imithelela pH amanani angaphansi kuka-7,4 emzimbeni womuntu

I-Acidosis yisimo esibangelwa ukukhiqizwa ngokweqile kwe-asidi enqwabelana egazini noma ukulahlekelwa ngokweqile kwe-bicarbonate (metabolic acidosis). Ngokufanayo, kungabangelwa ukunqwabelana kwe-carbon dioxide okubangelwa ukungasebenzi kahle kwamaphaphu (i-acidosis yokuphefumula).

• I-pH ephansi noma ene-asidi iphinde ibangele umzimba ukuthi ugcine i-asidi emangqamuzaneni ethu amafutha, okuholela ekukhiqizeni amangqamuzana amafutha amaningi (into yokugcina esiyidingayo!). ngakho… ngokubuyisela umzimba wakho ezingeni le-pH elifanele, sivumela imizimba yethu ukuthi ilahlekelwe amangqamuzana amafutha angafuneki.
• Ukucindezeleka, ukuntuleka kokuzivocavoca umzimba kanye nemikhuba yokudla engeyinhle kwehlisa i-pH yegazi futhi kungaholela ezifweni.
• Ukudla okune-asidi kuthathwa njenge-pH engaphansi kuka-4,6 futhi kufanele kugwenywe, okuhlanganisa iziphuzo ezibandayo, ukudla okugayiwe, inhlanzi, ushukela, okusanhlamvu, nenyama egayiwe.
• Eqinisweni, i-pH ephansi noma ene-asidi ingenye yezimbangela ezibaluleke kakhulu zezifo eziningi, njengomdlavuza, isibonelo, njengoba kutholakale ukuthi ama-85% eziguli ezinomdlavuza anamazinga e-pH aphakathi kuka-5 no-6.

I-Alkalosis: Ukungalingani kwamanani avamile wezempilo

• I-Alkalosis yisimo esihlanganisa i-alkalinity eyeqile egazini ebangelwa ukuchichima kwe-bicarbonate noma ukulahleka kwe-asidi (i-metabolic alkalosis). Kungase futhi kubangelwe izinga eliphansi le-carbon dioxide egazini elibangelwa ukuphefumula okusheshayo noma okujulile (i-respiratory alkalosis). Nakuba ingavamile kakhulu kune-acidosis, i-alkalosis iphinde ibangele ukungalingani kwe-pH.

Ukuphazamiseka kwebhalansi ye-pH value impilo

Ukungalingani ph amanani ajwayelekile ezempilo

Ukungalingani kwenani le-pH impilo: ukuphazamiseka kwebhalansi ye-acid-base. i-alkalosis ye-metabolic kanye nokuphefumula.